Article

Mismatch repair deficiency is associated with specific morphologic features and frequent loss of ARID1A expression in ovarian clear cell carcinoma

2021-02-08

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Ovarian clear cell carcinoma (OCCC) is the second subtype of ovarian epithelial carcinoma reported to be closely related to Lynch syndrome (LS). ARID1A mutation is an important pathogenetic mechanism in OCCC that leads to loss of ARID1A expression in approximately half of OCCCs. However, the correlation of MMR status and ARID1A deficiency is unclear. The current...

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Literature Corpus work: 3a863cb6-1add-51d2-89e2-6a9f241b8cde
DOI: 10.21203/rs.3.rs-135227/v2

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