Article

Functional characterisation of driver events in ovarian clear cell carcinoma

2014-01-01

Abstract excerpt

Ovarian clear cell carcinoma (OCCC) is a distinct subtype of epithelial ovarian cancer (EOC) characterised by glycogen accumulation. Frequently arising within endometriotic cysts, it can be conceived as an ectopic endometrial cancer. Putative driver genomic events include HNF1B overexpression and inactivating ARID1A mutations. Importantly, these can also be found in a significant proportion of adjacent non-maligna...

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Literature Corpus work: a6908e68-9095-5d8c-8886-26f436e4f728
DOI: 10.17863/cam.15891

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