Article
[GABAC receptors: structure and functions].
Eksperimental'naia i klinicheskaia farmakologiia - 1 Jan 2011
Perfilova V N, Tiurenkov I N
Abstract excerpt
Data on the structure, localization, physiology and pharmacology of GABA(C) receptors are reviewed. Thece receptors belong to cys-loop receptors and consist of rho1-3 subunits representing pentamers with five subunits that form a chloride channel. They are found in both central nervous system and peripheral organs. The pentamer can be homomeric, consisting of five similar protomers (e.g., p1), or heteromeric...
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