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Article

GABA(A) receptors in the pontine reticular formation of C57BL/6J mouse modulate neurochemical, electrographic, and behavioral phenotypes of wakefulness.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Sept 2010

Flint RaShonda R, Chang Theresa, Lydic Ralph, Baghdoyan Helen A

Abstract excerpt

Drugs that potentiate transmission at GABA(A) receptors are widely used to enhance sleep and to cause general anesthesia. The mechanisms underlying these effects are unknown. This study tested the hypothesis that GABA(A) receptors in the pontine reticular nucleus, oral part (PnO) of mouse modulate five phenotypes of arousal: sleep and wakefulness, cortical electroencephalogram (EEG) activity, acetylcholine (ACh)...

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Identifiers

PMID: 20844126
DOI: 10.1523/JNEUROSCI.1119-10.2010
PMCID: PMC2952114

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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