Article

Differential CpG methylation at <i>Nnat</i> in the early establishment of beta cell heterogeneity

2023-02-04

Abstract excerpt

<h4>Aims/hypothesis</h4> Beta cells within the pancreatic islet represent a heterogenous population wherein individual sub-groups of cells make distinct contributions to the overall control of insulin secretion. These include a subpopulation of highly-connected ‘hub’ cells, important for the propagation of intercellular Ca 2+ waves. Functional subpopulations have also been demonstrated in human beta cells, with...

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Literature Corpus work: d4a3b4c0-2d97-5079-9097-1083a13129c0
DOI: 10.1101/2023.02.04.527050

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