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Article

DNA Methylation Patterning and the Regulation of Beta Cell Homeostasis.

Frontiers in endocrinology - 1 Jan 2021

Parveen Nazia, Dhawan Sangeeta

Abstract excerpt

Pancreatic beta cells play a central role in regulating glucose homeostasis by secreting the hormone insulin. Failure of beta cells due to reduced function and mass and the resulting insulin insufficiency can drive the dysregulation of glycemic control, causing diabetes. Epigenetic regulation by DNA methylation is central to shaping the gene expression patterns that define the fully functional beta cell phenotype...

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Identifiers

PMID: 34025578
DOI: 10.3389/fendo.2021.651258
PMCID: PMC8137853

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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