Article

Occludin regulates HIV-1 infection by modulation of the interferon stimulated OAS gene family

2023-01-30

Abstract excerpt

<title>Abstract</title> <p>HIV-1-associated blood brain barrier (BBB) alterations and neurocognitive disorders are frequent clinical manifestations in HIV-1 infected patients. The BBB is formed by cells of the neurovascular unit (NVU) and sealed together by tight junction (TJ) proteins, such as occludin (ocln). Pericytes are a key cell type of NVU that can harbor HIV-1 infection via a mechanism that is regulated,...

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Literature Corpus work: d48d7e98-9706-5125-ba28-d95881ac874c
DOI: 10.21203/rs.3.rs-2501091/v1

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