Article

Brain tissue transcriptomic analysis of SIV-infected macaques identifies Poly (ADP-ribose) polymerases (PARPs) as potential biomarkers for neuropathogenesis.

2020-05-28

Abstract excerpt

<title>Abstract</title> <p>Background. Despite improvements in antiretroviral therapy, human immunodeficiency virus type 1 (HIV-1)-associated neurocognitive disorders (HAND) remain prevalent in subjects undergoing therapy. HAND significantly affects individuals’ quality of life, as well as adherence to therapy, and, despite the increasing understanding of neuropathogenesis, no definitive diagnostic or prognostic...

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Literature Corpus work: 6b0aa0aa-91a9-5257-bc6b-dcd7d9ab661c
DOI: 10.21203/rs.3.rs-30629/v1

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