Article

Cerebrospinal fluid immune cells appear similar across neuropathic and non-neuropathic pain conditions

2023-10-25

Abstract excerpt

Background Microglia have been implicated in the pathophysiology of neuropathic pain. Here, we sought to investigate whether cerebrospinal fluid (CSF) might be used as a proxy-measure of microglial activation in human participants. Methods We preformed fluorescence-activated cell sorting (FACS) of CSF immune cell populations derived from individuals who experienced pain with neuropathic features. We sorted CD4+, C...

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Literature Corpus work: d4743080-6fbf-5f14-99a0-31e7748c709b
DOI: 10.12688/wellcomeopenres.20153.1

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