Article

Neuroinflammatory Biomarkers in Chronic Low Back Pain: Mechanisms, Clinical Evidence, and Translational Challenges

2026-02-02

Abstract excerpt

<h4>Background: </h4> Chronic low back pain (CLBP) is a leading cause of disability worldwide and remains clinically challenging due to its marked heterogeneity and limited correlation between structural pathology and symptoms. Increasing evidence suggests that neuroinflammatory mechanisms and central sensitization (CS) contribute to pain persistence in a clinically relevant subset of patients. This narrative revi...

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Literature Corpus work: 586cd17a-7890-5cc0-a5e5-aa40da88b2bc
DOI: 10.20944/preprints202602.0057.v1

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