Article

Nerve-targeting and pain-promoting transcriptomic signatures in early Guillain-Barré syndrome

2025-09-25

Abstract excerpt

Guillain-Barré syndrome (GBS) is an autoimmune disorder that causes weakness, sensory loss, autonomic dysfunction, and chronic neuropathic pain. The mediators responsible for driving early autoimmune injury in the most common GBS variant, acute inflammatory demyelinating polyradiculoneuropathy (AIDP), remain incompletely understood. We performed single-cell and bulk RNA sequencing on peripheral blood mononuclear c...

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Literature Corpus work: 310473df-0cae-58dc-b0e1-a8c1f4201049
DOI: 10.1101/2025.09.24.678413

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