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Article

Ex vivo anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotyping.

Communications biology - 21 Jan 2022

Sachs Laura, Wesche Jan, Lenkeit Lea, Greinacher Andreas, Bender Markus, Otto Oliver, Palankar Raghavendra

Abstract excerpt

Inherited platelet disorders affecting the human platelet cytoskeleton result in increased bleeding risk. However, deciphering their impact on cytoskeleton-dependent intrinsic biomechanics of platelets remains challenging and represents an unmet need from a diagnostic and prognostic perspective. It is currently unclear whether ex vivo anticoagulants used during collection of peripheral blood impact the...

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Identifiers

PMID: 35064207
DOI: 10.1038/s42003-021-02982-6
PMCID: PMC8782918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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