Article
Associating the phenotypic expression of platelets with disease type through image-based single-cell profiling.
Thrombosis research - 1 Jul 2026
Wang Huidong, Nishikawa Masako, Zhou Yuqi, Yang Ruoxi, Chen Junyu, Zhang Hongqian, Ibayashi Yuma, Kanno Hiroshi, Kurano Makoto, Morishita Eriko, Yatomi Yutaka, Goda Keisuke
Abstract excerpt
BACKGROUND: Platelets are central to hemostasis and thrombosis and contribute to diverse diseases, including cardiovascular disorders, infections, and cancer. Although platelet activation and dysfunction in disease have been studied extensively, disease-associated platelet phenotypes remain poorly defined, largely because phenotypic changes are subtle, transient, and difficult to capture at single-cell...
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