Article

Integrative modeling of tumor DNA methylation identifies a role for metabolism

2016-06-07

Abstract excerpt

DNA methylation varies across genomic regions, tissues and individuals in a population. Altered DNA methylation is common in cancer and often considered an early event in tumorigenesis. However, the sources of heterogeneity of DNA methylation among tumors remain poorly defined. Here, we capitalize on the availability of multi-platform data on thousands of molecularly-and clinically-annotated human tumors to build...

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Literature Corpus work: d44a9ccd-ac59-57af-9dfc-ae4166596e5b
DOI: 10.1101/057638

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