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Article

Metabolic Dysregulations and Epigenetics: A Bidirectional Interplay that Drives Tumor Progression

30 Jul 2019

Abstract excerpt

Cancer has been considered, for a long time, a genetic disease where mutations in keyregulatory genes drive tumor initiation, growth, metastasis, and drug resistance. Instead, theadvent of high-throughput technologies has revolutionized cancer research, allowing to investigatemolecular alterations at multiple levels, including genome, epigenome, transcriptome, proteome,and metabolome and showing the multifaceted...

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PMID: 31366176
DOI: 10.3390/cells8080798

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