Article

Charting the cross-functional map between transcription factors and cancer metabolism

2018-01-19

Abstract excerpt

Transcriptional reprogramming of cellular metabolism is a hallmark feature of cancer. However, a systematic approach to study the role of transcription factors (TFs) in mediating cancer metabolic rewiring is missing. Here, we chart a genome-scale map of TF-metabolite associations in human using a new combined computational-experimental framework for large-scale metabolic profiling of adherent cell lines, and the i...

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Literature Corpus work: 2cf6f22d-4324-585c-bda5-ce6354d69f7e
DOI: 10.1101/250399

Open publication

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