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Article

Gene Expression Integration into Pathway Modules Reveals a Pan-Cancer Metabolic Landscape.

Cancer research - 1 Nov 2018

Cubuk Cankut, Hidalgo Marta R, Amadoz Alicia, Pujana Miguel A, Mateo Francesca, Herranz Carmen, Carbonell-Caballero Jose, Dopazo Joaquin

Abstract excerpt

Metabolic reprogramming plays an important role in cancer development and progression and is a well-established hallmark of cancer. Despite its inherent complexity, cellular metabolism can be decomposed into functional modules that represent fundamental metabolic processes. Here, we performed a pan-cancer study involving 9,428 samples from 25 cancer types to reveal metabolic modules whose individual or...

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PMID: 30135189
DOI: 10.1158/0008-5472.CAN-17-2705

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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