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Alzheimer’s disease-associated β-Amyloid does not protect against Herpes Simplex Virus 1 brain infection

2021-01-22

Abstract excerpt

Alzheimer’s disease (AD) is devastating fatal neurodegenerative disease. An alternative to the amyloid cascade hypothesis is the hypothesis that a viral infection is key to the etiology of late-onset AD, with amyloid Aβ peptides playing a protective role. Contrary to previous work, in the current study the 5XFAD genotype failed to protect mice against infection with two strains of herpes simplex virus 1 (HSV-1), 1...

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Literature Corpus work
d3edafa1-7a5b-5bb2-a826-5bc3d307f87b
DOI
10.1101/2021.01.21.427570
Open publication

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Alzheimer’s disease-associated β-Amyloid does not protect against Herpes Simplex Virus 1 brain infectionDOI 10.1101/2021.01.21.427570
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