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Article

Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques.

The Journal of pathology - 1 Jan 2009

Wozniak M A, Mee A P, Itzhaki R F

Abstract excerpt

The brains of Alzheimer's disease sufferers are characterized by amyloid plaques and neurofibrillary tangles. However, the cause(s) of these features and those of the disease are unknown, in sporadic cases. We previously showed that herpes simplex virus type 1 is a strong risk factor for Alzheimer's disease when in the brains of possessors of the type 4 allele of the apolipoprotein E gene (APOE-epsilon4), and...

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Source

Identifiers

PMID: 18973185
DOI: 10.1002/path.2449

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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