Article

Cell-specific models of hiPSC-CMs developed by the gradient-based parameter optimization method fitting two different action potential waveforms

2023-12-11

Abstract excerpt

Parameter optimization (PO) methods to determine the ionic current composition of experimental cardiac action potential (AP) waveform have been developed using a computer model of cardiac membrane excitation. However, it was suggested that fitting a single AP record in the PO method was not always successful in providing a unique answer because of a shortage of information. We found that the PO method worked perfe...

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Literature Corpus work: d3ac51c6-42ca-582d-9639-6789552cdc45
DOI: 10.21203/rs.3.rs-3705784/v1

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Cell-specific models of hiPSC-CMs developed by the gradient-based parameter optimization method fitting two different action potential waveformsDOI 10.21203/rs.3.rs-3705784/v1Read

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