Article

Identifying drug response by combining measurements of the membrane potential, the cytosolic calcium concentration, and the extracellular potential in microphysiological systems

2020-05-31

Abstract excerpt

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) offer a new means to study and understand the human cardiac action potential, and can give key insight into how compounds may interact with important molecular pathways to destabilize the electrical function of the heart. Important features of the action potential can be readily measured using standard experimental techniques, such as the...

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Literature Corpus work: 4463406c-254e-568d-b63d-57b075322f1b
DOI: 10.1101/2020.05.29.122747

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