Article

Topology of the U12-U6atac snRNA complex of the minor spliceosome and binding by NTC-related protein RBM22

2019-10-31

Abstract excerpt

<h4>ABSTRACT</h4> Splicing of precursor messenger RNA is catalyzed by the spliceosome, a dynamic ribonucleoprotein assembly composed of five small nuclear (sn)RNAs and >100 proteins. RNA components catalyze the two transesterification reactions, but proteins perform critical roles in assembly and rearrangement. The catalytic core comprises a paired complex involving U2 and U6 snRNAs for the major form of the spli...

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Literature Corpus work: d375e257-4836-5fee-863c-ccc7d8e74b0d
DOI: 10.1101/825604

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