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Unified Mouse and Human Kidney Single-Cell Expression Atlas Reveal Commonalities and Differences in Disease States

2023-08-28

Abstract excerpt

Significance Statement Mouse models have been widely used to understand kidney disease pathomechanisms and play an important role in drug discovery. However, these models have not been systematically analyzed and compared. The authors characterized 18 different mouse kidney disease models at both bulk and single-cell gene expression levels and compared single-cell gene expression data from diabetic kidney disease...

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Literature Corpus work
96805be2-03d7-500e-8403-0740c29b7c01
DOI
10.1681/asn.0000000000000217
Open publication

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Unified Mouse and Human Kidney Single-Cell Expression Atlas Reveal Commonalities and Differences in Disease StatesDOI 10.1681/asn.0000000000000217
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