Article

A Landscape of Genetic and Cellular Hallmarks in Chronic Kidney Disease

2024-07-16

Abstract excerpt

<title>Abstract</title> <p>Chronic kidney disease (CKD) affects >800 million individuals worldwide, while spatiotemporal inventory of CKD hallmarks is lacking. Here, we comprehensively map the landscape of 18,740 genes, 24,604 genesets, and 19 cell types in a mouse CKD model, using spatial RNA sequencing and <italic>in vivo</italic> two-photon imaging. Unsupervised transcriptome clustering identifies seven spatia...

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Literature Corpus work: 1e0cb92e-3d33-5522-a67b-b1984827a6ab
DOI: 10.21203/rs.3.rs-4681754/v1

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