Article

The Dynamic Nature of Genetic Risk for Schizophrenia Within Genes Regulated by <i>FOXP1</i> During Neurodevelopment

2025-05-13

Abstract excerpt

FOXP1 (Forkhead-box protein P1) is a crucial transcription factor in neural development and is associated with schizophrenia (SCZ). FOXP1 -regulated genes may contribute to genetic risk of SCZ and this may vary across different stages of neurodevelopment. We analyzed transcriptomic data from mouse and human models of FOXP1 loss-of-function across prenatal and postnatal developmental stages, including neural stem...

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Literature Corpus work: 283afc18-699b-5ca0-a29d-30391bea74cc
DOI: 10.1101/2025.05.12.653444

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