Article

FOXP1 regulates the development of excitatory synaptic inputs onto striatal neurons and induces phenotypic reversal with reinstatement

2023-10-24

Abstract excerpt

<h4>Summary</h4> Long-range glutamatergic inputs from the cortex and thalamus are critical for motor and cognitive processing in the striatum. Transcription factors that orchestrate the development of these inputs are largely unknown. We investigated the role of a transcription factor and high-risk autism-associated gene, FOXP1, in the development of glutamatergic inputs onto spiny projection neurons (SPNs) in th...

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Literature Corpus work: 69f83cf9-c614-5e07-aeff-3541b7334484
DOI: 10.1101/2023.10.23.563675

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