Article
Role of regulatory T cell in the pathogenesis of inflammatory bowel disease.
World journal of gastroenterology - 21 Feb 2016
Yamada Akiko, Arakaki Rieko, Saito Masako, Tsunematsu Takaaki, Kudo Yasusei, Ishimaru Naozumi
Abstract excerpt
Regulatory T (Treg) cells play key roles in various immune responses. For example, Treg cells contribute to the complex pathogenesis of inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis during onset or development of that disease. Many animal models of IBD have been used to investigate factors such as pathogenic cytokines, pathogenic bacteria, and T-cell functions, including...
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