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High plasma IL-18 identifies high-risk ARDS patients not identified by latent class analysis sub-phenotyping: a secondary analysis of the SAILS and HARP-2 studies

2022-11-17

Abstract excerpt

<h4>Background: </h4> Both latent class analysis (LCA) assignment based upon a panel of plasma biomarkers and interleukin-18 (IL-18) plasma level have been shown to predict prognosis and treatment response in Acute Respiratory Distress Syndrome (ARDS). Interleukin-18 is a measure of inflammasome activation and plays a distinct role in inflammation that is not captured by the biomarkers used in LCA assignments. We...

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Literature Corpus work
d32167a8-d124-5b50-8133-c60cfe726a29
DOI
10.21203/rs.3.rs-2256911/v1
Open publication

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High plasma IL-18 identifies high-risk ARDS patients not identified by latent class analysis sub-phenotyping: a secondary analysis of the SAILS and HARP-2 studiesDOI 10.21203/rs.3.rs-2256911/v1
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