Article

Inflammatory sub-phenotypes in sepsis: relationship to outcomes, treatment effect and transcriptomic sub-phenotypes

2022-07-12

Abstract excerpt

<h4>Rationale</h4> Heterogeneity of sepsis limits discovery and targeting of treatments. Clustering approaches in critical illness have identified patient groups who may respond differently to therapies. These include in acute respiratory distress syndrome (ARDS) two inflammatory sub-phenotypes, using latent class analysis (LCA), and in sepsis two Sepsis Response Signatures (SRS), based on transcriptome profiling....

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Literature Corpus work: 44b6d0ec-ca80-59be-a770-9103a7542d02
DOI: 10.1101/2022.07.12.22277463

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