Article
Prevalence of phenotypes of acute respiratory distress syndrome in critically ill patients with COVID-19: a prospective observational study.
The Lancet. Respiratory medicine - 1 Dec 2020
Sinha Pratik, Calfee Carolyn S, Cherian Shiney, Brealey David, Cutler Sean, King Charles, Killick Charlotte, Richards Owen, Cheema Yusuf, Bailey Catherine, Reddy Kiran, Delucchi Kevin L, Shankar-Hari Manu, Gordon Anthony C, Shyamsundar Murali, O'Kane Cecilia M, McAuley Daniel F, Szakmany Tamas
Abstract excerpt
BACKGROUND: In acute respiratory distress syndrome (ARDS) unrelated to COVID-19, two phenotypes, based on the severity of systemic inflammation (hyperinflammatory and hypoinflammatory), have been described. The hyperinflammatory phenotype is known to be associated with increased multiorgan failure and mortality. In this study, we aimed to identify these phenotypes in COVID-19-related ARDS. METHODS: In this...
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