Article
Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials.
The Lancet. Respiratory medicine - 1 Aug 2014
Calfee Carolyn S, Delucchi Kevin, Parsons Polly E, Thompson B Taylor, Ware Lorraine B, Matthay Michael A
Abstract excerpt
BACKGROUND: Subphenotypes have been identified within heterogeneous diseases such as asthma and breast cancer, with important therapeutic implications. We assessed whether subphenotypes exist within acute respiratory distress syndrome (ARDS), another heterogeneous disorder. METHODS: We used data from two ARDS randomised controlled trials (ARMA trial and ALVEOLI trial), sponsored by the National Heart, Lung, and...
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