Subphenotypes in acute respiratory distress syndrome: A scoping review across clinical, biological, computational, imaging, omics, and artificial intelligence approaches.

Abstract excerpt

BACKGROUND: Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome with high mortality. Subphenotyping may identify more homogeneous groups for prognostic enrichment and precision therapies. METHODS: We conducted a scoping review (January 2013-December 31, 2025) in PubMed, Embase, and the Cochrane Library, complemented by reference screening. We included original adult studies deriving, applying,...

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