Article

Quantifying tumor specificity using Bayesian probabilistic modeling for drug target discovery and prioritization

2023-03-06

Abstract excerpt

In diseases such as cancer, the design of new therapeutic strategies requires extensive, costly, and unfortunately sometimes deadly testing to reveal life threatening off target effects. A crucial first step in predicting toxicity are analyses of normal RNA and protein tissue expression, which are now possible using comprehensive molecular tissue atlases. However, no standardized approaches exist for target priori...

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Literature Corpus work: d3214680-d1d9-57a0-b1d3-3827bce5df0c
DOI: 10.1101/2023.03.03.530994

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