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A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities for therapeutic target identification and evaluation

2018-04-30

Abstract excerpt

Differences in the expression of genes and their splice isoforms across human tissues are fundamental factors to consider for therapeutic target evaluation. To this end, we conducted a transcriptome-wide survey of tissue-specific gene expression and splicing events in the unprecedented collection of 8527 high-quality RNA-seq samples from the GTEx project, covering 36 human peripheral tissues and 13 brain subregion...

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Literature Corpus work
85c3937c-61c1-5afa-8229-309212714dbb
DOI
10.1101/311563
Open publication

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A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities for therapeutic target identification and evaluationDOI 10.1101/311563
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