Article

Bioinformatics Analysis of Non-Coding UTR Variants in <i>STAT1</i> Reveals Disruption of miRNA Binding, mRNA Stability, and Oncogenic Potential

2025-01-18

Abstract excerpt

Single nucleotide polymorphisms (SNPs) are associated with a wide range of disorders, including diverse cancer types. In the context of cancer, alterations within non-coding regions, specifically untranslated regions (UTRs), have proven substantially important. SNPs localized in the 3 prime UTRs of the STAT1 gene were assessed for their association with miRNAs using PolymiRTS, miRNASNP, and MicroSNIper. In additi...

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Literature Corpus work: d2ff1181-108e-59e8-940e-4effe276eca6
DOI: 10.1101/2025.01.16.632379

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