Article

Sparse Modeling of Genomic Landscape Identifies Pathogenic Processes and Therapeutic Targets in Metastatic Breast Cancer

2023-08-31

Abstract excerpt

<h4>ABSTRACT</h4> Breast cancer is a heterogeneous disease and ranks as one of the most lethal and frequently detected disease in the world. It poses significant challenges for precision therapy. To better decipher the patterns of heterogeneous nature in human genome and converge them into common functionals, mutational signatures are introduced to define the types of DNA damage, repair and replicative mechanisms...

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Literature Corpus work: d2ef5587-2465-5742-b374-22d16730b0b0
DOI: 10.1101/2023.08.29.554992

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