Article
Improving personalized prediction of cancer prognoses with clonal evolution models
2019-09-18
Abstract excerpt
Cancer occurs via an accumulation of somatic genomic alterations in a process of clonal evolution. There has been intensive study of potential causal mutations driving cancer development and progression. However, much recent evidence suggests that tumor evolution is normally driven by a variety of mechanisms of somatic hypermutability, known as mutator phenotypes, which act in different combinations or degrees in...
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Identifiers and source
- Literature Corpus work
- 9a05e22a-9e92-5437-b524-1b83b1125794
- DOI
- 10.1101/761510