Article

A δ-cell subpopulation with a pro-β-cell identity confers efficient age-independent recovery in a zebrafish model of diabetes

2021-06-24

Abstract excerpt

Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other pancreatic cells raises the questions of the efficiency of the process and of the functionality of the new Insulin -expressing cells. To overcome the weak regenerative capacity of mammals, we used regeneration-prone zebrafish to study β-cells arising following destruction. We show that most new in s ulin cells differ from the o...

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Literature Corpus work: d2bf131a-396d-5d28-92f3-52d8d05959e2
DOI: 10.1101/2021.06.24.449706

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