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A single-cell atlas of <i>de novo</i> β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish

2021-06-24

Abstract excerpt

Regeneration-competent species possess the ability to reverse the progression of severe diseases by restoring the function of the damaged tissue. However, the cellular dynamics underlying this capability remain unexplored. Here, we use single-cell transcriptomics to map de novo β-cell regeneration during induction and recovery from diabetes in zebrafish. We show that the zebrafish has evolved two distinct types o...

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Identifiers and source

Literature Corpus work
028cb431-2faf-538e-9ea5-7ef09adc5949
DOI
10.1101/2021.06.24.449704
Open publication

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A single-cell atlas of <i>de novo</i> β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafishDOI 10.1101/2021.06.24.449704
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