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Article

Vertical sleeve gastrectomy triggers fast β-cell recovery upon overt diabetes

6 Sept 2021

Abstract excerpt

OBJECTIVE: The effectiveness of bariatric surgery in restoring β-cell function has been described in type-2 diabetes (T2D) patients and animal models for years, whereas the mechanistic underpinnings are largely unknown. The possibility of vertical sleeve gastrectomy (VSG) to rescue far-progressed, clinically-relevant T2D and to promote β-cell recovery has not been investigated on a single-cell level....

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PMID: 34500108
DOI: 10.1016/j.molmet.2021.101330

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