Article

IGFBP3-mediated M2 Macrophage Polarization Enhances Resistance to Rosiglitazone and Cisplatin in Breast Cancer

2024-11-01

Abstract excerpt

<title>Abstract</title> <p>Background Rosiglitazone (PPARγ agonist, RGZ) combined with chemotherapy drugs has proven effective in treating clinical breast cancer patients. However, the underlying targets and resistance mechanisms remain unclear, posing challenges in maintaining long-term efficacy. This study aimed to investigate the mechanisms of RGZ in macrophage polarization and evaluate its effects within the...

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Literature Corpus work: d28ebd38-f701-569c-bf08-cc3bbefa341b
DOI: 10.21203/rs.3.rs-5174260/v1

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IGFBP3-mediated M2 Macrophage Polarization Enhances Resistance to Rosiglitazone and Cisplatin in Breast CancerDOI 10.21203/rs.3.rs-5174260/v1Read

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