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Article

Tumor-Associated Macrophages: Critical Players in Drug Resistance of Breast Cancer.

Frontiers in immunology - 1 Jan 2021

Xiao Maoyu, He Jun, Yin Liyang, Chen Xiguan, Zu Xuyu, Shen Yingying

Abstract excerpt

Drug resistance is one of the most critical challenges in breast cancer (BC) treatment. The occurrence and development of drug resistance are closely related to the tumor immune microenvironment (TIME). Tumor-associated macrophages (TAMs), the most important immune cells in TIME, are essential for drug resistance in BC treatment. In this article, we summarize the effects of TAMs on the resistance of various drugs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34992609
DOI: 10.3389/fimmu.2021.799428
PMCID: PMC8724912

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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