Article

Secreted HLA Fc-Fusion Profiles Immunopeptidome in Hypoxic PDAC and Cellular Senescence

2023-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Human leukocyte antigens (HLA) display peptides largely from intracellular proteins on the surface of cells in major histocompatibility complex (MHC)-peptide complexes. These complexes provide a biological window into the cell, and peptides derived from disease-associated antigens can serve as biomarkers and therapeutic targets. Thus, proper identification of peptides and the corresponding prese...

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Literature Corpus work: 2319c8b0-debe-5195-ab00-1c65d60c6a99
DOI: 10.1101/2023.04.10.536290

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