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Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Using Cell-Free DNA 5-Hydroxymethylation Signatures

2021-12-29

Abstract excerpt

<h4>BACKGROUND</h4> Pancreatic cancer (PaC) has poor (10%) 5-year overall survival, largely due to predominant late-stage diagnosis. Patients with new-onset diabetes (NOD) are at a six-to eightfold increased risk for PaC. We developed a pancreatic cancer detection test for the use in a clinical setting that employs a logistic regression model based on 5-hydroxymethylcytosine (5hmC) profiling of cell-free DNA (cfDN...

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Literature Corpus work
d26f6c18-458e-5af5-a554-a786cdac3c63
DOI
10.1101/2021.12.27.21268450
Open publication

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Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Using Cell-Free DNA 5-Hydroxymethylation SignaturesDOI 10.1101/2021.12.27.21268450
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