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Circulating cell‐free <scp>DNA</scp> methylation‐based multi‐omics analysis allows early diagnosis of pancreatic ductal adenocarcinoma

1 Apr 2024

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer with a 5-year survival rate of 7.2% in China. However, effective approaches for diagnosis of PDAC are limited. Tumor-originating genomic and epigenomic aberration in circulating free DNA (cfDNA) have potential as liquid biopsy biomarkers for cancer diagnosis. Our study aims to assess the feasibility of cfDNA-based liquid biopsy assay for PDAC...

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PMID: 38561976
DOI: 10.1002/1878-0261.13643

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