Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancer

23 Jul 2020

Abstract excerpt

BACKGROUND: The high lethal rate of pancreatic cancer is partly due to a lack of efficient biomarkers for screening and early diagnosis. We attempted to develop effective and noninvasive methods using 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) markers from circulating cell-free DNA (cfDNA) for the detection of pancreatic ductal adenocarcinoma (PDAC). RESULTS: A 24-feature 5mC model that can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32703318
DOI: 10.1186/s13148-020-00898-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated epigenetic biomarkers in circulating cell-free DNA as a robust classifier for pancreatic cancerPMID 32703318Read ↗

Circulating cell‐free <scp>DNA</scp> methylation‐based multi‐omics analysis allows early diagnosis of pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Genome-Wide Analysis of Cell-Free DNA Methylation Profiling for the Early Diagnosis of Pancreatic CancerSemantic proximity Read ↗

Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNASemantic proximity Read ↗

Development and Validation of a Cell-Free DNA Fragmentomics–Based Model for Early Detection of Pancreatic CancerSemantic proximity Read ↗

A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer.Semantic proximity Read ↗

Circulating cell-free DNA methylation analysis of pancreatic cancer patients for early noninvasive diagnosisSemantic proximity Read ↗

Noninvasive detection of pancreatic ductal adenocarcinoma using the methylation signature of circulating tumour DNASemantic proximity Read ↗

Cell-Free DNA Methylation: The New Frontiers of Pancreatic Cancer Biomarkers’ DiscoverySemantic proximity Read ↗

Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNASemantic proximity Read ↗

Circulating Cell-Free DNA fragmentomics distinguishes pancreatic ductal adenocarcinoma from non- malignant conditionsSemantic proximity Read ↗

Cell-free DNA promoter hypermethylation as a diagnostic marker for pancreatic ductal adenocarcinoma – An external validation studySemantic proximity Read ↗

Validation of a Pancreatic Cancer Detection Test in New-Onset Diabetes Using Cell-Free DNA 5-Hydroxymethylation SignaturesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.