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Article

Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA

2018-09-20

Abstract excerpt

Pancreatic cancers are typically diagnosed at late stage where disease prognosis is poor as exemplified by a 5-year survival rate of 8.2%. Earlier diagnosis would be beneficial by enabling surgical resection or earlier application of therapeutic regimens. We investigated the detection of pancreatic ductal adenocarcinoma (PDAC) in a non-invasive manner by interrogating changes in 5-hydroxymethylation cytosine statu...

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Literature Corpus work
dd292ec4-d408-5e26-9c46-386c4ebf120e
DOI
10.1101/422675
Open publication

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Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNADOI 10.1101/422675
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