Article

Time-dependent BMP4 signaling directs lineage specification in human mesoderm

2026-07-05

Abstract excerpt

<h4>ABSTRACT</h4> Human pluripotent stem cells (hPSCs) provide a powerful platform for modeling early human embryonic development. Here, we investigate the mechanisms underlying mesodermal heterogeneity using a minimal directed differentiation system that simultaneously generates paraxial (PXM), intermediate (IM) and lateral plate mesoderm (LPM) populations. Single-cell RNA sequencing across defined time points d...

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Literature Corpus work: d25306c5-e5c3-58bf-8a77-e54d9d6916b5
DOI: 10.64898/2026.07.03.736254

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