Article
Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning.
Genome biology - 1 Jan 2007
Doss Michael Xavier, Chen Shuhua, Winkler Johannes, Hippler-Altenburg Rita, Odenthal Margareta, Wickenhauser Claudia, Balaraman Sridevi, Schulz Herbert, Hummel Oliver, Hübner Norbert, Ghosh-Choudhury Nandini, Sotiriadou Isaia, Hescheler Jürgen, Sachinidis Agapios
Abstract excerpt
BACKGROUND: Bone morphogenetic protein (BMP)2 is a late mesodermal marker expressed during vertebrate development and plays a crucial role in early embryonic development. The nature of the BMP2-expressing cells during the early stages of embryonic development, their transcriptome and cell phenotypes developed from these cells have not yet been characterized. RESULTS: We generated a transgenic BMP2 embryonic stem...
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