Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells

1 Apr 2020

Abstract excerpt

Recent studies using human pluripotent stem cells (hPSCs) have developed protocols to induce kidney-lineage cells and reconstruct kidney organoids. However, the separate generation of metanephric nephron progenitors (NPs), mesonephric NPs, and ureteric bud (UB) cells, which constitute embryonic kidneys, in in vitro differentiation culture systems has not been fully investigated. Here, we create a culture system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Organ Donation and Transplantation
Share to Pluripotent Stem Cells Research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32268094
DOI: 10.1016/j.celrep.2020.03.040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem CellsPMID 32268094Read ↗

Mouse Embryonic Stem Cell-Derived Ureteric Bud Progenitors Induce NephrogenesisSemantic proximity Read ↗

Generating kidney organoids based on developmental nephrologySemantic proximity Read ↗

Ureteric Bud Cells Programmed from Embryonic Stem Cells Obtain Competence for Secondary Induction in the KidneySemantic proximity Read ↗

Kidney organoids: Research in developmental biology and emerging applicationsSemantic proximity Read ↗

Generation of kidney ureteric bud and collecting duct organoids that recapitulate kidney branching morphogenesisSemantic proximity Read ↗

A developmentally-inspired hypoxia condition promotes kidney organoid differentiation from human pluripotent stem cellsSemantic proximity Read ↗

Human pluripotent stem cell-derived kidney organoids: Current progress and challengesSemantic proximity Read ↗

A strategy for generating kidney organoids: Recapitulating the development in human pluripotent stem cellsSemantic proximity Read ↗

The origin of the mammalian kidney: implications for recreating the kidney <i>in vitro</i>Semantic proximity Read ↗

Concise Review: Kidney Generation with Human Pluripotent Stem CellsSemantic proximity Read ↗

Differentiation of Human Pluripotent Stem Cells into Nephron Progenitor Cells in a Serum and Feeder Free SystemSemantic proximity Read ↗

Cellular and Molecular Mechanisms of Kidney Development: From the Embryo to the Kidney OrganoidSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.